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diphepanol
Sign in to saveDiphepanol is a cough suppressant (antitussive).
Chemical data
- Formula
- C20H25NO
- Molecular weight
- 295.4 g/mol
- IUPAC name
- 1,1-diphenyl-2-piperidin-1-ylpropan-1-ol
- SMILES
- CC(C(C1=CC=CC=C1)(C2=CC=CC=C2)O)N3CCCCC3
- InChIKey
- ZOCMPVMKPVJTEP-UHFFFAOYSA-N
- XLogP
- 3.9
- Polar surface area
- 23.5 Ų
- H-bond donors
- 1
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 295.194
Show 3 more facts
- chemical formula
- C₂₀H₂₅NO
- canonical SMILES
- CC(C(C1=CC=CC=C1)(C2=CC=CC=C2)O)N3CCCCC3
- Commons category
- Diphepanol
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Synthesis
- See also
- References
Diphepanol is a cough suppressant (antitussive).
==Synthesis== thumb|center|500px|Synthesis: Patent: Ex 1: The α-keto bromination of propiophenone [93-55-0] (1) gives 2-bromopropiophenone [2114-00-3] (2). Displacement of the halogen and hence amination with piperidine [110-89-4] gave alpha-Piperidinopropiophenone, CID:458526 (3). and addition of phenyl Grignard reagent to give the benzhydrol product, and hence Dihepanol (4).
Excerpted from Wikipedia’s “diphepanol” article, available under the CC BY-SA 4.0 licence.