DLL3
Sign in to saveAlso known as SCDO1, pu, pudgy, delta like canonical Notch ligand 3
Delta-like 3 (Drosophila), also known as DLL3, is a protein which in humans is encoded by the DLL3 gene. Two transcript variants encoding distinct isoforms have been identified for this gene.
Gene data
DLL3- Name
- delta like canonical Notch ligand 3
- Type
- protein-coding
- Position
- 39,498,895–39,508,481 (+)
- Aliases
- SCDO1
- Ensembl
- ENSG00000090932
- RefSeq RNA
- NM_016941.4, NM_203486.3
- RefSeq protein
- NP_058637.1, NP_982353.1
This gene encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutations in this gene cause autosomal recessive spondylocostal dysostosis 1. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
delta like canonical Notch ligand 3
- Symbol
- DLL3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:39,498,895-39,508,481
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 7291
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/10683
- genomic end
- 39999121
- genomic start
- 39989535
- chromosome
- human chromosome 19
- cytogenetic location
- 19q13.2
- expressed in
- putamen
via Wikidata · CC0
~1 min read
Encyclopedic overview
5 sectionsContents
- Function
- Clinical significance
- References
- External links
- Further reading
Delta-like 3 (Drosophila), also known as DLL3, is a protein which in humans is encoded by the DLL3 gene. Two transcript variants encoding distinct isoforms have been identified for this gene.
== Function ==
Excerpted from Wikipedia’s “DLL3” article, available under the CC BY-SA 4.0 licence.