DLL4

Also known as hdelta2, AOS6, delta like canonical Notch ligand 4, delta4

Delta-like 4 is a protein that in humans is encoded by the DLL4 gene.

Gene data

DLL4

Name: delta like canonical Notch ligand 4
Type: protein-coding
Position: 40,929,333–40,939,081 (+)
Aliases: AOS6, delta4, hdelta2
Ensembl: ENSG00000128917
RefSeq RNA: NM_019074.4
RefSeq protein: NP_061947.1

This gene is a homolog of the Drosophila delta gene. The delta gene family encodes Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. [provided by RefSeq, Jul 2008].

Pathways

Notch signaling pathway - Homo sapiens (human)Th1 and Th2 cell differentiation - Homo sapiens (human)Pathways in cancer - Homo sapiens (human)Breast cancer - Homo sapiens (human)Signaling by NOTCH Signaling by NOTCH Signal Transduction Signal Transduction Disease Signaling by NOTCH1

via MyGene.info

Gene · Ensembl

delta like canonical Notch ligand 4

Symbol: DLL4
Biotype: Protein coding
Organism: Homo sapiens
Location: 15:40,929,333-40,939,081
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 9 more facts

HomoloGene ID: 10411
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/54567
genomic end: 40939073
genomic start: 40929340
chromosome: human chromosome 15
cytogenetic location: 15q15.1
genetic association: Adams-Oliver syndrome
expressed in: cardia

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Encyclopedic overview

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References
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Delta-like 4 is a protein that in humans is encoded by the DLL4 gene.

This gene is a homolog of the Drosophila delta gene. The delta gene family encodes Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain.

Excerpted from Wikipedia’s “DLL4” article, available under the CC BY-SA 4.0 licence.