DNAJC28
Sign in to saveAlso known as C21orf55, C21orf78, DnaJ heat shock protein family (Hsp40) member C28
DnaJ homolog subfamily C member 28 is a protein that in humans is encoded by the DNAJC28 gene. It's a member of chaperone DnaJ family. The family is also known as Hsp40 (heat shock protein 40 kDa).
Gene data
DNAJC28- Name
- DnaJ heat shock protein family (Hsp40) member C28
- Type
- protein-coding
- Aliases
- C21orf55, C21orf78
This gene encodes a member of the DnaJ heat shock protein family. The encoded protein, which contains a conserved N-terminal DnaJ domain, is thought to play a role in protein folding or act as a molecular chaperone protein. [provided by RefSeq, Oct 2016].
via MyGene.info
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 9869
- exact match
- identifiers.org/ncbigene/54943
- genomic start
- 34860497
- genomic end
- 33491716
- cytogenetic location
- 21q22.11
Sources (4)
via Wikidata · CC0
~12 min read
Article
13 sectionsContents
- Gene
- RNA and Transcriptional variants
- Protein
- Conserved Regions
- Tertiary Structure
- Interacting Proteins
- Orthologs
- Localization and Expression
- Function
- Clinical significance
- References
- External links
- Further reading
DnaJ homolog subfamily C member 28 is a protein that in humans is encoded by the DNAJC28 gene. It's a member of chaperone DnaJ family. The family is also known as Hsp40 (heat shock protein 40 kDa).
== Gene == thumb|DNAJC28 human gene location with surrounding genes. IFNGR2 encodes the beta chain of the gamma interferon receptor, and defects in it cause extreme immunodeficiency. TMEM50B is hypothesized to be involved in endosome to vacuole transportation. Neighboring GART is involved in de novo purine synthesis. SON encodes a protein that binds RNA, promotes pre-mRNA splicing, and recognizes a human Hepatitis B virus DNA sequence, repressing its core promoter activity. The DNAJC28 gene is located on the negative strand of Chromosome 21 (21q22.11), spanning 3,784 base pairs. Also known as C21orf78 or (previously) C21orf55 in humans, this gene has orthologs in animals, plants, and fungi. DNAJC28 has only 2 exons, the first of which is the only one that differs between transcript variants.