DPP10
Sign in to saveAlso known as DPL2, DPPY, DPRP-3, DPRP3, dipeptidyl peptidase like 10
Inactive dipeptidyl peptidase 10 is a protein that in humans is encoded by the DPP10 gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Gene data
DPP10- Name
- dipeptidyl peptidase like 10
- Type
- protein-coding
- Position
- 114,442,299–115,845,794 (+)
- Aliases
- DPL2, DPPY, DPRP-3, DPRP3
- Ensembl
- ENSG00000175497
- RefSeq RNA
- NM_001004360.5, NM_001178034.1, NM_001178036.3, NM_001178037.3, NM_001321905.3
- RefSeq protein
- NP_001004360.3, NP_001171505.1, NP_001171507.2, NP_001171508.2, NP_001308834.2
This gene encodes a single-pass type II membrane protein that is a member of the S9B family in clan SC of the serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Mutations in this gene have been associated with asthma. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
dipeptidyl peptidase like 10
- Symbol
- DPP10
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 2:114,442,299-115,845,794
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 41400
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/57628
- genomic end
- 115845780
- genomic start
- 115199876
- expressed in
- amygdala
- chromosome
- human chromosome 2
- cytogenetic location
- 2q14.1
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- Clinical significance
- References
- Further reading
Inactive dipeptidyl peptidase 10 is a protein that in humans is encoded by the DPP10 gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
== Function ==
Excerpted from Wikipedia’s “DPP10” article, available under the CC BY-SA 4.0 licence.