EHMT2
Sign in to saveAlso known as BAT8, C6orf30, G9A, GAT8, KMT1C, NG36, euchromatic histone lysine methyltransferase 2
istone metiltransferasi che nell'uomo è codificato dal gene EHMT2
Gene data
EHMT2- Name
- euchromatic histone lysine methyltransferase 2
- Type
- protein-coding
- Chromosome
- HSCHR6_MHC_QBL_CTG1
- Position
- 3,135,732–3,153,671 (−)
- Aliases
- BAT8, C6orf30, G9A, GAT8, KMT1C, NG36
- Ensembl
- ENSG00000232045
- RefSeq RNA
- NM_001289413.2, NM_001318833.2, NM_001363689.2, NM_001395160.1, NM_001395161.1
- RefSeq protein
- NP_001276342.1, NP_001305762.1, NP_001350618.1, NP_001382089.1, NP_001382090.1
This gene encodes a methyltransferase that methylates lysine residues of histone H3. Methylation of H3 at lysine 9 by this protein results in recruitment of additional epigenetic regulators and repression of transcription. This gene was initially thought to be two different genes, NG36 and G9a, adjacent to each other in the HLA locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
euchromatic histone lysine methyltransferase 2
- Symbol
- EHMT2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- Chr HSCHR6_MHC_MCF_CTG1:3,221,824-3,239,759
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein EHMT2 PDB 2o8j.png
Show 8 more facts
- HomoloGene ID
- 48460
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/10919
- chromosome
- human chromosome 6
- genomic start
- 31847536
- genomic end
- 31865464
- cytogenetic location
- 6p21.33
- expressed in
- anterior cingulate cortex
Sources (4)
via Wikidata · CC0
Article · Italiano
L'EHMT2 [( in inglese Euchromatic istone-lisina N-metiltransferasi 2, noto anche come G9a, è un istone metiltransferasi che nell'uomo è codificato dal gene EHMT2.
Abstract from DBpedia / Wikipedia · CC BY-SA