Structure via PubChem · Public domain (PubChem)
emoxypine
Sign in to saveEmoxypine (2-ethyl-6-methyl-3-hydroxypyridine), also known as Mexidol or Mexifin, a succinate salt, is chemical compound which is claimed by its manufacturer, the Russian company Pharmasoft Pharmaceuticals, to have antioxidant and actoprotector properties, but these purported properties of emoxypine have not been proven. Its chemical structure resembles that of pyridoxine (a type of vitamin B6).
Chemical data
- Formula
- C8H11NO
- Molecular weight
- 137.18 g/mol
- IUPAC name
- 2-ethyl-6-methylpyridin-3-ol
- SMILES
- CCC1=C(C=CC(=N1)C)O
- InChIKey
- JPGDYIGSCHWQCC-UHFFFAOYSA-N
- XLogP
- 1.7
- Polar surface area
- 33.1 Ų
- H-bond donors
- 1
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 3
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
478 papers- Promising effects of emoxypine and its succinate derivative in the management of various diseases-with insights on recent patent applications.Current research in pharmacology and drug discovery · 2022
- Emoxypine succinate modulates behavioral and molecular responses in zebrafish model of iron Overload-Induced neuroinflammation via CDK5/GSK3- β and NLRP3 inflammasome pathway.Brain research · 2025
- Pharmaceutical salts of emoxypine with dicarboxylic acids.Acta crystallographica. Section C, Structural chemistry · 2018
- Emoxypine as a Potential Marker for Identifying Possible Cases of Unintended Meldonium Doping in Sports.Drug testing and analysis · 2026
- [The effect of rubomycin, mexidol and emoxypine on some metabolic indexes and the proccess of spontaneous metastasis under conditions of experimental neoplasia].Eksperimental'naia i klinicheskaia farmakologiia · 2007
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Has part
- carbon
- Mass
- 137.084
Show 5 more facts
via Wikidata · CC0
~4 min read
Encyclopedic overview
8 sectionsContents
- History
- Use
- Mechanism of action
- Clinical study
- Legal status
- See also
- References
- External links
Emoxypine (2-ethyl-6-methyl-3-hydroxypyridine), also known as Mexidol or Mexifin, a succinate salt, is chemical compound which is claimed by its manufacturer, the Russian company Pharmasoft Pharmaceuticals, to have antioxidant and actoprotector properties, but these purported properties of emoxypine have not been proven. Its chemical structure resembles that of pyridoxine (a type of vitamin B6).
==History== Emoxypine was first synthesized by L.D. Smirnov and K.M. Dumayev, then studied and developed in the Russian Institute of Pharmacology, Russian Academy of Medical Sciences and Russian Scientific Center of Bioactive Substances Safety. Its research and use has been largely isolated to former soviet states, with little interest from other countries.
Excerpted from Wikipedia’s “emoxypine” article, available under the CC BY-SA 4.0 licence.