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Sign in to saveAlso known as antigenic epitope, epitopes
An epitope, also known as antigenic determinant, is the part of an antigen that is recognized by the immune system, specifically by antibodies, B cells, or T cells. The part of an antibody that binds to the epitope is called a paratope. Although epitopes are usually non-self proteins, sequences derived from the host that can be recognized (as in the case of autoimmune diseases) are also epitopes.
Research
186,651 papers- Glycosylation of bacterial antigens changes epitope patterns.Frontiers in immunology · 2023
- High throughput functional epitope mapping: revisiting phage display platform to scan target antigen surface.mAbs · 2014
- Cross-reactive SARS-CoV-2 epitope targeted across donors informs immunogen design.Cell reports. Medicine · 2022
- Circumscribing the conformational peptide epitope landscape.Current pharmaceutical design · 2012
- Epitope Identification and Affinity Determination of an Inhibiting Human Antibody to Interleukin IL8 (CXCL8) by SPR- Biosensor-Mass Spectrometry Combination.Journal of the American Society for Mass Spectrometry · 2020
via PubMed