Structure via PubChem · Public domain (PubChem)
estrone
Sign in to saveAlso known as Aquest®, Kestrone®, oestrone, follicular hormone, folliculin, (8R,9S,13S,14S)-3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one, 3-Hydroxyoestra-1,3,5(10)-trien-17-one, D1,3,5(10)-Estratrien-3-ol-17-one
composto chimico
Chemical data
- Formula
- C18H22O2
- Molecular weight
- 270.4 g/mol
- IUPAC name
- (8R,9S,13S,14S)-3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one
- SMILES
- C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)CCC4=C3C=CC(=C4)O
- InChIKey
- DNXHEGUUPJUMQT-CBZIJGRNSA-N
- XLogP
- 3.1
- Polar surface area
- 37.3 Ų
- H-bond donors
- 1
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1979
- Admin. routes
- parenteral
- Indications
- obesity, premenstrual tension
via ChEMBL · EBI
Research
16,684 papers- Palladium-catalyzed cross-coupling reactions of estrone.Steroids · 2025
- Distinct roles of estrone and estradiol in endothelial colony-forming cells.Physiological reports · 2023
- Endocrine effects of masturbation in men.The Journal of endocrinology · 1976
- Synthesis, functionalization and biological activity of arylated derivatives of (+)-estrone.Bioorganic & medicinal chemistry · 2017
- Solvent-dependent fluorescence lifetimes of estrone, 17β-estradiol and 17α-ethinylestradiol.Photochemistry and photobiology · 2013
via PubMed
Wikidata facts
- Has part
- carbon
- Mass
- 270.162
- Has use
- medication
Show 10 more facts
- chemical formula
- C₁₈H₂₂O₂
- canonical SMILES
- CC12CCC3C(C1CCC2=O)CCC4=C3C=CC(=C4)O
- World Health Organisation international non-proprietary name
- estrone
- subject has role
- primary metabolite
- found in taxon
- Phoenix dactylifera
- defined daily dose
- 1
- isomeric SMILES
- C[C@]12CC[C@H]3[C@@H](CCC4=CC(O)=CC=C34)[C@@H]1CCC2=O
- NCI Thesaurus ID
- C484
- melting point
- 259
- Commons category
- Estrone
Sources (8)
via Wikidata · CC0