FBXO4

Also known as FBX4, F-box protein 4

F-box only protein 4 is a protein that in humans is encoded by the FBXO4 gene.

In the Vinony graph

Within Vinony's link graph, FBXO4 is referenced by 3 other articles, and connects out to Q180686, human chromosome 5 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 5.

Its subject is documented across 5 Wikipedia language editions.

Gene data

FBXO4

Name: F-box protein 4
Type: protein-coding
Position: 41,925,210–42,040,243 (+)
Aliases: FBX4
Ensembl: ENSG00000151876
RefSeq RNA: NM_001297437.2, NM_012176.3, NM_033484.3, XM_011514026.4, XM_011514027.3
RefSeq protein: NP_001284366.1, NP_036308.1, NP_277019.1, XP_011512328.1, XP_011512329.1

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014].