FBXO7

Name

F-box protein 7

Type

protein-coding

Position

32,474,676–32,499,787 (+)

Aliases

FBX, FBX07, FBX7, PARK15, PKPS

Ensembl

ENSG00000100225

RefSeq RNA

NM_001033024.2, NM_001257990.2, NM_012179.4

RefSeq protein

NP_001028196.1, NP_001244919.1, NP_036311.3

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it may play a role in regulation of hematopoiesis. Alternatively spliced transcript variants of this gene have been identified with the full-length natures of only some variants being determined. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

F-box protein 7

Symbol

FBXO7

Biotype

Protein coding

Organism

Homo sapiens

Location

22:32,474,676-32,499,787

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

Instance of

gene

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