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flavoprotein

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Also known as Flavoproteins, flavin enzyme, yellow enzyme

Flavoproteins are proteins that contain a nucleic acid derivative of riboflavin. These proteins are involved in a wide array of biological processes, including removal of radicals contributing to oxidative stress, photosynthesis, and DNA repair. The flavoproteins are some of the most-studied families of enzymes.

Key facts

Protein family.Symbol
Flavoprotein
Protein family.Name
Flavoprotein
Protein family.image
PDB 1e20 EBI.jpg
Protein family.caption
the fmn binding protein athal3
Protein family.Pfam
PF02441
Protein family.InterPro
IPR003382
Protein family.SCOP
1e20

via Wikipedia infobox

Research

66,503 papers

via PubMed

~4 min read

Article

4 sections
Contents
  • Discovery
  • Examples
  • References
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Flavoproteins are proteins that contain a nucleic acid derivative of riboflavin. These proteins are involved in a wide array of biological processes, including removal of radicals contributing to oxidative stress, photosynthesis, and DNA repair. The flavoproteins are some of the most-studied families of enzymes.

Flavoproteins have either FMN (flavin mononucleotide) or FAD (flavin adenine dinucleotide) as a prosthetic group or as a cofactor. The flavin is generally tightly bound (as in adrenodoxin reductase, wherein the FAD is buried deeply). About 5-10% of flavoproteins have a covalently linked FAD. Based on the available structural data, FAD-binding sites can be divided into more than 200 different types.

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