GIGYF2
Sign in to saveAlso known as GYF2, PARK11, PERQ2, PERQ3, TNRC15, GRB10 interacting GYF protein 2
PERQ amino acid-rich with GYF domain-containing protein 2 is a protein that in humans is encoded by the GIGYF2 gene.
Gene data
GIGYF2- Name
- GRB10 interacting GYF protein 2
- Type
- protein-coding
- Position
- 232,697,259–232,863,338 (+)
- Aliases
- GYF2, PARK11, PERQ2, PERQ3, TNRC15
- Ensembl
- ENSG00000204120
- RefSeq RNA
- NM_001103146.3, NM_001103147.2, NM_001103148.2, NM_015575.4, NR_103492.1
- RefSeq protein
- NP_001096616.1, NP_001096617.1, NP_001096618.1, NP_056390.2
This gene contains CAG trinucleotide repeats and encodes a protein containing several stretches of polyglutamine residues. The encoded protein may be involved in the regulation of tyrosine kinase receptor signaling. This gene is located in a chromosomal region that was genetically linked to Parkinson disease type 11, and mutations in this gene were thought to be causative for this disease. However, more recent studies in different populations have been unable to replicate this association. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
GRB10 interacting GYF protein 2
- Symbol
- GIGYF2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 2:232,697,259-232,863,338
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
PERQ amino acid-rich with GYF domain-containing protein 2 is a protein that in humans is encoded by the GIGYF2 gene.
==References==
Excerpted from Wikipedia’s “GIGYF2” article, available under the CC BY-SA 4.0 licence.