ZNF598
Sign in to saveAlso known as zinc finger protein 598, HEL2, zinc finger protein 598, E3 ubiquitin ligase
Zinc finger protein 598 (ZNF598) is a protein that in humans is encoded by the ZNF598 gene.
Gene data
ZNF598- Name
- zinc finger protein 598, E3 ubiquitin ligase
- Type
- protein-coding
- Aliases
- HEL2
Zinc-finger proteins bind nucleic acids and play important roles in various cellular functions, including cell proliferation, differentiation, and apoptosis. This protein and Grb10-interacting GYF protein 2 have been identified as a components of the mammalian 4EHP (m4EHP) complex. The complex is thought to function as a translation repressor in embryonic development. [provided by RefSeq, Oct 2012].
via MyGene.info
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 5672
- exact match
- identifiers.org/ncbigene/90850
- genomic end
- 2009821
- genomic start
- 2047655
- cytogenetic location
- 16p13.3
Sources (4)
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Article
2 sectionsContents
- Function
- References
Zinc finger protein 598 (ZNF598) is a protein that in humans is encoded by the ZNF598 gene.
== Function == Zinc-finger proteins bind nucleic acids and play important roles in various cellular functions, including cell proliferation, differentiation, and apoptosis. This protein and Grb10-interacting GYF protein 2 have been identified as a components of the mammalian 4EHP (m4EHP) complex. The complex is thought to function as a translation repressor in embryonic development. ZNF598 and its yeast homologue Hel2 are ubiquitin ligases that ubiquitinate the 40S ribosomal subunit during ribosome-associated protein quality control.