GLRX3
Sign in to saveAlso known as GLRX4, GRX3, GRX4, PICOT, TXNL2, TXNL3, glutaredoxin 3
Glutaredoxin-3 is a protein that in humans is encoded by the GLRX3 gene.
Gene data
GLRX3- Name
- glutaredoxin 3
- Type
- protein-coding
- Position
- 130,136,363–130,184,521 (+)
- Aliases
- GLRX4, GRX3, GRX4, PICOT, TXNL2, TXNL3
- Ensembl
- ENSG00000108010
- RefSeq RNA
- NM_001199868.2, NM_001321980.2, NM_006541.5
- RefSeq protein
- NP_001186797.1, NP_001308909.1, NP_006532.2
This gene encodes a member of the glutaredoxin family. Glutaredoxins are oxidoreductase enzymes that reduce a variety of substrates using glutathione as a cofactor. The encoded protein binds to and modulates the function of protein kinase C theta. The encoded protein may also inhibit apoptosis and play a role in cellular growth, and the expression of this gene may be a marker for cancer. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 9. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
glutaredoxin 3
- Symbol
- GLRX3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 10:130,136,363-130,184,521
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 4769
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/10539
- chromosome
- human chromosome 10
- genomic start
- 130136391
- genomic end
- 131982785
- cytogenetic location
- 10q26.3
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Interactions
- References
- Further reading
- External links
Glutaredoxin-3 is a protein that in humans is encoded by the GLRX3 gene.
==Interactions== GLRX3 has been shown to interact with PRKCQ.
Excerpted from Wikipedia’s “GLRX3” article, available under the CC BY-SA 4.0 licence.