hexahydrocannabinol
Sign in to saveAlso known as 6,6,9-Trimethyl-3-pentyl-6a,7,8,9,10,10a-hexahydro-6H-dibenzo[b,d]pyran-1-ol, HHC
Hexahydrocannabinol (HHC) is a phytocannabinoid that has been reported as a trace component of Cannabis sativa. It can also be synthesized by hydrogenation of tetrahydrocannabinol (THC). The synthesis and bioactivity of HHC was first reported in 1940 by Roger Adams.
Key facts
- Drug.IUPAC_name
- (6aR,10aR)-6,6,9-trimethyl-3-pentyl-6a,7,8,9,10,10a-hexahydrobenzo[c]chromen-1-ol
- Drug.image
- Hexahydrocannabinol.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 220
- Drug.image2
- HHC 3D BS.png
- Drug.image_class2
- bg-transparent
- Drug.width2
- 220
- Drug.legal_UK
- Illegal to produce, supply, or sell under the Psychoactive Substances Act 2016
- Drug.legal_US
- Unscheduled
- Drug.legal_UN
- Unscheduled
- Drug.legal_status
- In general legal.
- Drug.CAS_number
- 6692-85-9
- Drug.CAS_supplemental
- (unspecified stereochemistry)946512-74-9 (6aR,10aR)
- Drug.ATC_prefix
- None
- Drug.PubChem
- 16050328
- Drug.ChemSpiderID
- 13178711
- Drug.C
- 21
- Drug.H
- 32
via Wikipedia infobox
Wikidata facts
- Subclass of
- cannabinoids
- Mass
- 316.24023026399993
Show 3 more facts
- canonical SMILES
- CCCCCC1=CC(=C2C3CC(CCC3C(OC2=C1)(C)C)C)O
- Commons category
- Hexahydrocannabinol
- chemical formula
- C₂₁H₃₂O₂
via Wikidata · CC0
~7 min read
Encyclopedic overview
5 sectionsContents
- Pharmacology
- Chemistry
- Legality
- See also
- References
Hexahydrocannabinol (HHC) is a phytocannabinoid that has been reported as a trace component of Cannabis sativa. It can also be synthesized by hydrogenation of tetrahydrocannabinol (THC). The synthesis and bioactivity of HHC was first reported in 1940 by Roger Adams.
HHC is a psychoactive substance with effects reportedly similar to those of THC. HHC vaporizers have been openly sold at head shops and convenience stores since at least the early 2020s in North America and Europe. While HHC has never been approved by any drug regulatory agency, a racemic mixture of epimers has shown in vitro activity against pancreatic ductal adenocarcinoma cell lines.
Excerpted from Wikipedia’s “hexahydrocannabinol” article, available under the CC BY-SA 4.0 licence.