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hexamethyldisiloxane
Sign in to saveAlso known as HMDSO, ((CH3)3Si)2O, oxybis(trimethylsilane), bis(trimethylsilyl) ether, bis(trimethylsilyl) oxide
Hexamethyldisiloxane (HMDSO or MM) is an organosilicon compound with the formula O[Si(CH3)3]2, often abbreviated O[SiMe3]2. This volatile colourless liquid is used as a solvent and as a reagent in organic synthesis. It is prepared by the hydrolysis of trimethylsilyl chloride. The molecule is the protypical disiloxane and resembles a subunit of polydimethylsiloxane.
Chemical data
- Formula
- C6H18OSi2
- Molecular weight
- 162.38 g/mol
- IUPAC name
- trimethyl(trimethylsilyloxy)silane
- SMILES
- C[Si](C)(C)O[Si](C)(C)C
- InChIKey
- UQEAIHBTYFGYIE-UHFFFAOYSA-N
- Polar surface area
- 9.2 Ų
- H-bond donors
- 0
- H-bond acceptors
- 1
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
Show 4 more facts
- chemical formula
- C₆H₁₈OSi₂
- canonical SMILES
- C[Si](C)(C)O[Si](C)(C)C
- melting point
- -67.0
- Commons category
- Hexamethyldisiloxane
via Wikidata · CC0
~3 min read
Encyclopedic overview
4 sectionsContents
- Synthesis and reactions
- Solvent-related uses
- Other
- References
Hexamethyldisiloxane (HMDSO or MM) is an organosilicon compound with the formula O[Si(CH3)3]2, often abbreviated O[SiMe3]2. This volatile colourless liquid is used as a solvent and as a reagent in organic synthesis. It is prepared by the hydrolysis of trimethylsilyl chloride. The molecule is the protypical disiloxane and resembles a subunit of polydimethylsiloxane.
==Synthesis and reactions== Hexamethyldisiloxane can be produced by the addition of trimethylsilyl chloride to purified water:
Excerpted from Wikipedia’s “hexamethyldisiloxane” article, available under the CC BY-SA 4.0 licence.