HEXIM2
Sign in to saveAlso known as L3, hexamethylene bisacetamide inducible 2, HEXIM P-TEFb complex subunit 2
gene umano
Gene data
HEXIM2- Name
- HEXIM P-TEFb complex subunit 2
- Type
- protein-coding
- Position
- 45,160,695–45,170,701 (+)
- Aliases
- L3
- Ensembl
- ENSG00000168517
- RefSeq RNA
- NM_001303436.1, NM_001303437.1, NM_001303438.1, NM_001303439.1, NM_001303440.2
- RefSeq protein
- NP_001290365.1, NP_001290366.1, NP_001290367.1, NP_001290368.1, NP_001290369.1
This gene encodes a member of the HEXIM family of proteins. This protein is a component of the 7SK small nuclear ribonucleoprotein. This protein has been found to negatively regulate the kinase activity of the cyclin-dependent kinase P-TEFb, which phosphorylates multiple target proteins to promote transcriptional elongation. This gene is located approximately 7 kb downstream from related family member HEXIM1 on chromosome 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015].
Gene Ontology
Biological process
Molecular function
Cellular component
via MyGene.info
Gene · Ensembl
HEXIM P-TEFb complex subunit 2
- Symbol
- HEXIM2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:45,160,695-45,170,701
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 16946
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/124790
- genomic end
- 43247407
- genomic start
- 43238067
- chromosome
- human chromosome 17
- cytogenetic location
- 17q21.31
Sources (4)
via Wikidata · CC0