HEXIM2

Also known as L3, hexamethylene bisacetamide inducible 2, HEXIM P-TEFb complex subunit 2

gen de la especie Homo sapiens

In the Vinony graph

Within Vinony's link graph, HEXIM2 is referenced by 5 other articles, and connects out to PubMed, human chromosome 17 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 17.

Its subject is documented across 6 Wikipedia language editions.

Gene data

HEXIM2

Name: HEXIM P-TEFb complex subunit 2
Type: protein-coding
Position: 45,160,695–45,170,701 (+)
Aliases: L3
Ensembl: ENSG00000168517
RefSeq RNA: NM_001303436.1, NM_001303437.1, NM_001303438.1, NM_001303439.1, NM_001303440.2
RefSeq protein: NP_001290365.1, NP_001290366.1, NP_001290367.1, NP_001290368.1, NP_001290369.1

This gene encodes a member of the HEXIM family of proteins. This protein is a component of the 7SK small nuclear ribonucleoprotein. This protein has been found to negatively regulate the kinase activity of the cyclin-dependent kinase P-TEFb, which phosphorylates multiple target proteins to promote transcriptional elongation. This gene is located approximately 7 kb downstream from related family member HEXIM1 on chromosome 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015].