Structure via PubChem · Public domain (PubChem)
Hippuristanol
Sign in to saveHippuristanol is a small molecule found in the coral Isis hippuris which was discovered by Jerry Pelletier and others of McGill University in Montreal, Quebec, Canada. It appears to have anti-viral activity and may hold promise as a cancer therapy. Binds to and inhibits the eukaryotic translation initiation factor protein eIF4A.
Chemical data
- Formula
- C28H46O5
- Molecular weight
- 462.7 g/mol
- IUPAC name
- 2',2',3',7,9,13-hexamethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icosane-6,5'-oxolane]-7,11,16-triol
- SMILES
- CC1CC2(C(C3C(O2)CC4C3(CC(C5C4CCC6C5(CCC(C6)O)C)O)C)(C)O)OC1(C)C
- InChIKey
- HPHXKNOXVBFETI-UHFFFAOYSA-N
- XLogP
- 4.2
- Polar surface area
- 79.2 Ų
- H-bond donors
- 3
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Mass
- 462.334524572
Show 4 more facts
- Commons category
- Hippuristanol
- chemical formula
- C₂₈H₄₆O₅
- isomeric SMILES
- [H][C@@]23CC[C@@]1([H])C[C@H](O)CC[C@@](C)1[C@]([H])2[C@@H](O)C[C@@]4(C)[C@@](C[C@@]5([H])[C@@]([H])4[C@](O)(C)[C@]6(C[C@H](C)C(C)(C)O6)O5)3[H]
- canonical SMILES
- OC1CCC2(C)C(CCC3C4CC5OC6(OC(C)(C)C(C)C6)C(O)(C)C5C4(C)CC(O)C32)C1
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Hippuristanol is a small molecule found in the coral Isis hippuris which was discovered by Jerry Pelletier and others of McGill University in Montreal, Quebec, Canada. It appears to have anti-viral activity and may hold promise as a cancer therapy. Binds to and inhibits the eukaryotic translation initiation factor protein eIF4A.
==See also== Eukaryotic translation eIF4A
Excerpted from Wikipedia’s “Hippuristanol” article, available under the CC BY-SA 4.0 licence.