SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related is a protein that in humans is encoded by the HMG20B gene.
Predicted to enable DNA binding activity. Predicted to be involved in regulation of gene expression. Predicted to act upstream of or within negative regulation of protein sumoylation; positive regulation of neuron differentiation; and skeletal muscle cell differentiation. Located in nuclear body. [provided by Alliance of Genome Resources, Apr 2022]
via MyGene.info
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related is a protein that in humans is encoded by the HMG20B gene.
HMG20B is a high-mobility group (HMG) DNA binding protein. HMG20B contains a carboxy terminal region that is essential for cytokinesis since it regulates cell cycle progression from the G2 phase into mitosis This carboxy terminal region of HMG20B interacts with the tumor suppressor protein BRCA2. A particular mutation in this region of the HMG20B gene is associated with lung cancer. This mutation interferes with the association of the HMG20B and BRCA2 proteins.
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).