HOMER1
Sign in to saveAlso known as HOMER, HOMER1A, HOMER1B, HOMER1C, SYN47, Ves-1, homer scaffolding protein 1, homer scaffold protein 1
Homer protein homolog 1 or Homer1 is a neuronal protein that in humans is encoded by the HOMER1 gene. Other names are Vesl and PSD-Zip45.
Gene data
HOMER1- Name
- homer scaffold protein 1
- Type
- protein-coding
- Position
- 79,372,636–79,514,565 (−)
- Aliases
- HOMER, HOMER1A, HOMER1B, HOMER1C, SYN47, Ves-1
- Ensembl
- ENSG00000152413
- RefSeq RNA
- NM_001277077.1, NM_001277078.1, NM_004272.5, XM_017010059.3, XM_047417894.1
- RefSeq protein
- NP_001264006.1, NP_001264007.1, NP_004263.1, XP_016865548.1, XP_047273850.1
This gene encodes a member of the homer family of dendritic proteins. Members of this family regulate group 1 metabotrophic glutamate receptor function. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
phospholipase C-activating G protein-coupled glutamate receptor signaling pathwayG protein-coupled glutamate receptor signaling pathwayG protein-coupled glutamate receptor signaling pathwaychemical synaptic transmissionpositive regulation of signal transductionprotein tetramerizationresponse to calcium ionregulation of synaptic transmission, glutamatergic
Molecular function
Pathways
FoxO signaling pathway - Homo sapiens (human)Glutamatergic synapse - Homo sapiens (human)Neuronal SystemNeuronal SystemNeurexins and neuroliginsNeurexins and neuroliginsProtein-protein interactions at synapsesProtein-protein interactions at synapsesBDNF-TrkB SignalingSynaptic signaling pathways associated with autism spectrum disorder
via MyGene.info
Gene · Ensembl
homer scaffold protein 1
- Symbol
- HOMER1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 5:79,372,124-79,514,573
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein HOMER1 PDB 1ddv.png
Show 5 more facts
- HomoloGene ID
- 3155
- exact match
- identifiers.org/ncbigene/9456
- genomic end
- 79514134
- genomic start
- 78668459
- cytogenetic location
- 5q14.1
Sources (3)
via Wikidata · CC0
~3 min read
Article
7 sectionsContents
- Structure
- Tissue distribution
- Function
- Rapid antidepressant effects
- See also
- References
- Further reading
Homer protein homolog 1 or Homer1 is a neuronal protein that in humans is encoded by the HOMER1 gene. Other names are Vesl and PSD-Zip45.
== Structure ==
Connections
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