hydrogen bond
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AI overview
A hydrogen bond is a weak attraction that forms between a hydrogen atom (attached to an electronegative atom like oxygen or nitrogen) and another electronegative atom nearby. These bonds are important because they influence how molecules interact with each other, affecting properties like the boiling point of water and the structure of proteins.
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Research
140,742 papers- Hydrogen-Bond Donors in Drug Design.Journal of medicinal chemistry · 2022
- Muon disrupts AKT hydrogen bond network in cancer.Journal of cellular physiology · 2019
- Dynamic hydrogen-bond networks in bacterial protein secretion.FEMS microbiology letters · 2018
- Hydrogen Bond Assisted Three-Component Tandem Reactions to Access N-Alkyl-4-Quinolones.Molecules (Basel, Switzerland) · 2023
- Organo-Polyoxometalate-Based Hydrogen-Bond Catalysis.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021
via PubMed
Article
Model of hydrogen bonds (1) between molecules of water AFM image of naphthalenetetracarboxylic diimide molecules on silver-terminated silicon, interacting via hydrogen bonding, taken at 77 K. ("Hydrogen bonds" in the top image are exaggerated by artifacts of the imaging technique.)
In chemistry, a hydrogen bond (H-bond) is a specific type of molecular interaction that exhibits partial covalent character and cannot be described as a purely electrostatic force. It occurs when a hydrogen (H) atom, covalently bonded to a more electronegative donor atom or group (Dn), interacts with another electronegative atom bearing a lone pair of electrons—the hydrogen bond acceptor (Ac). Unlike simple dipole–dipole interactions, hydrogen bonding arises from charge transfer (nB → σ*AH), orbital interactions, and quantum mechanical delocalization, making it a resonance-assisted interaction rather than a mere electrostatic attraction.