hypoestrogenism
Sign in to saveAlso known as Estrogen deficiency, Oestrogen deficiency
Hypoestrogenism, or estrogen deficiency, refers to a lower than normal level of estrogen. It is an umbrella term used to describe estrogen deficiency in various conditions. Estrogen deficiency is also associated with an increased risk of cardiovascular disease, and has been linked to diseases like urinary tract infections and osteoporosis.
Clinical Trials
8 registered- PHASE1UNKNOWNStudy to Investigate the Pharmacokinetics & Safety Following One Application of 3 Different Doses 0.5,0.75,& 1.25 gm,a Transdermal Estradiol Cream (VML-0203), in Comparison to a Single Dose of EstroGel 1.25 gm to Healthy Post-menopausal Women.Viramal Limited · NCT03556800
- NACOMPLETEDPharmacokinetic Aspects of 25-mg Estradiol Pellet in Climacteric WomenScience Valley Research Institute · NCT06136208
- PHASE4RECRUITINGEstrogen Supplementation and Bone Health in Women With CFJohns Hopkins University · NCT05704036
- PHASE4ACTIVE_NOT_RECRUITINGAdherence to Vaginal Estrogen Therapy in Hypoestrogenic Women With Recurrent Urinary Tract InfectionsUniversity of California, Irvine · NCT06353269
- PHASE4COMPLETEDThe Kampala Women's Bone StudyUniversity of Washington · NCT03464266
- RECRUITINGENDO-BRAIN: Effects of Endocrine Adjuvant Therapy with Aromatase Inhibitors on the Cognitive Function of Breast Cancer PatientsOspedale Policlinico San Martino · NCT06606535
~11 min read
Article
16 sectionsContents
- Signs and symptoms
- Vasomotor
- Genitourinary
- Bone health
- Causes
- Risks
- Pathophysiology
- Diagnosis
- Menopause
- Functional hypothalamic amenorrhea
- Primary ovarian insufficiency
- Treatment
- In men
- See also
- References
- External links
Hypoestrogenism, or estrogen deficiency, refers to a lower than normal level of estrogen. It is an umbrella term used to describe estrogen deficiency in various conditions. Estrogen deficiency is also associated with an increased risk of cardiovascular disease, and has been linked to diseases like urinary tract infections and osteoporosis.
In women, low levels of estrogen may cause symptoms such as hot flashes, sleeping disturbances, decreased bone health, and changes in the genitourinary system. Hypoestrogenism is most commonly found in women who are postmenopausal, have primary ovarian insufficiency (POI), or are presenting with amenorrhea (absence of menstrual periods). Hypoestrogenism includes primarily genitourinary effects, including thinning of the vaginal tissue layers and an increase in vaginal pH. With normal levels of estrogen, the environment of the vagina is protected against inflammation, infections, and sexually transmitted infections. Hypoestrogenism can also occur in men, for instance due to hypogonadism.