IGF2BP3
Sign in to saveAlso known as CT98, IMP-3, IMP3, KOC, KOC1, VICKZ3, insulin like growth factor 2 mRNA binding protein 3
Insulin-like growth factor 2 mRNA-binding protein 3 is a protein that in humans is encoded by the IGF2BP3 gene.
Gene data
IGF2BP3- Name
- insulin like growth factor 2 mRNA binding protein 3
- Type
- protein-coding
- Position
- 23,310,209–23,470,491 (−)
- Aliases
- CT98, IMP-3, IMP3, KOC, KOC1, VICKZ3
- Ensembl
- ENSG00000136231
- RefSeq RNA
- NM_006547.3, XM_011515089.3, XM_011515090.4, XM_011515092.3, XM_011515093.3
- RefSeq protein
- NP_006538.2, XP_011513391.1, XP_011513392.1, XP_011513394.1, XP_011513395.1
The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Wikidata facts
- Image
- Protein IGF2BP3 PDB 2e44.png
Show 5 more facts
- HomoloGene ID
- 4773
- exact match
- identifiers.org/ncbigene/10643
- genomic end
- 23470491
- genomic start
- 23349828
- cytogenetic location
- 7p15.3
Sources (4)
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- See also
- References
- Further reading
Insulin-like growth factor 2 mRNA-binding protein 3 is a protein that in humans is encoded by the IGF2BP3 gene.
The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development.