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GeneQ18039852· pop 5· linked from 29 articles

Also known as IGK@, immunoglobulin kappa locus

Immunoglobulin kappa locus, also known as IGK@, is a region on the p arm of human chromosome 2, region 11.2 (2p11.2), that contains genes for the kappa (κ) light chains of antibodies (or immunoglobulins).

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Encyclopedic overview

3 sections
Contents
  • Genes
  • References
  • Further reading

Immunoglobulin kappa locus, also known as IGK@, is a region on the p arm of human chromosome 2, region 11.2 (2p11.2), that contains genes for the kappa (κ) light chains of antibodies (or immunoglobulins).

In humans the κ chain is coded for by V (variable), J (joining) and C (constant) genes in this region. These genes undergo V(D)J recombination to generate a diverse repertoire of immunoglobulins.

Excerpted from Wikipedia’s “IGK” article, available under the CC BY-SA 4.0 licence.

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