Integrón
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Integrons are genetic mechanisms that allow bacteria to adapt and evolve rapidly through the stockpiling and expression of new genes. These genes are embedded in a specific genetic structure called gene cassette (a term that is lately changing to integron cassette) that generally carries one promoterless open reading frame (ORF) together with a recombination site (attC). Integron cassettes are incorporated to the attI site of the integron platform by site-specific recombination reactions mediated by the integrase.
Research
5,271 papers- Integrons.Annual review of genetics · 2010
- Mobile integrons encode phage defense systems.Science (New York, N.Y.) · 2025
- Unbridled Integrons: A Matter of Host Factors.Cells · 2022
- Sedentary chromosomal integrons as biobanks of bacterial antiphage defense systems.Science (New York, N.Y.) · 2025
- Integrons: the hidden architects of bacterial adaptation, evolution, and the challenges of antimicrobial resistance.Antonie van Leeuwenhoek · 2025
via PubMed
Article · Español
Los integrones son mecanismos genéticos que permiten que las bacterias se adapten y evolucionen rápidamente a través del almacenamiento y la expresión génica. Estos genes están incrustados en una estructura genética específica llamada que generalmente lleva un marco de lectura abierto (ORF) sin promotor junto con un sitio de recombinación (attC). Los casetes de genes se incorporan al sitio attI de la plataforma mediante reacciones de recombinación específicas del sitio mediadas por la integrasa.
Abstract from DBpedia / Wikipedia · CC BY-SA