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isosafrole

Structure via PubChem · Public domain (PubChem)

EntityQ61738366· pop 21· linked from 37 articles

isosafrole

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Also known as 5-prop-1-enyl-1,3-benzodioxole

Isosafrole is an organic compound that is used in the fragrance industry. Structurally, the molecule is related to allylbenzene, a type of aromatic organic chemical. Its fragrance is reminiscent of anise or licorice. It is found in small amounts in various essential oils, but is most commonly obtained by isomerizing the plant oil safrole. It exists as two geometric isomers, cis-isosafrole and trans-isosafrole.

Chemical data

Formula
C10H10O2
Molecular weight
162.18 g/mol
IUPAC name
5-prop-1-enyl-1,3-benzodioxole
SMILES
CC=CC1=CC2=C(C=C1)OCO2
InChIKey
VHVOLFRBFDOUSH-UHFFFAOYSA-N
XLogP
3.1
Polar surface area
18.5 Ų
H-bond donors
0
H-bond acceptors
2
Formal charge
0

via PubChem

Wikidata facts

Mass
162.06807956
Show 3 more facts
Commons category
Isosafrole
canonical SMILES
CC=CC1=CC2=C(C=C1)OCO2
chemical formula
C₁₀H₁₀O₂
Sources (3)

via Wikidata · CC0

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Article

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Contents
  • References

Isosafrole is an organic compound that is used in the fragrance industry. Structurally, the molecule is related to allylbenzene, a type of aromatic organic chemical. Its fragrance is reminiscent of anise or licorice. It is found in small amounts in various essential oils, but is most commonly obtained by isomerizing the plant oil safrole. It exists as two geometric isomers, cis-isosafrole and trans-isosafrole.

Isosafrole is a precursor to the important fragrance piperonal. It can also be converted via the intermediate compound MDP2P into the psychoactive drug MDMA ('ecstasy'). As such it requires permits to purchase or sell in any significant quantity in the US.

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