Isosthenuria
Sign in to saveIsosthenuria refers to the excretion of urine whose specific gravity (concentration) is neither greater (more concentrated) nor less (more diluted) than that of protein-free plasma, typically 1.008-1.012. Isosthenuria reflects damage to the kidney's tubules or the renal medulla.
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- Clinical significance
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Isosthenuria refers to the excretion of urine whose specific gravity (concentration) is neither greater (more concentrated) nor less (more diluted) than that of protein-free plasma, typically 1.008-1.012. Isosthenuria reflects damage to the kidney's tubules or the renal medulla.
A closely related term is hyposthenuria, where the urine has a relatively low specific gravity "due to inability of the kidney to concentrate the urine normally". This specific gravity is not necessarily equal to that of plasma. Therefore, unlike isosthenuria, this condition is not associated with kidney failure as the kidney tubules have altered the glomerular filtrate.
Excerpted from Wikipedia’s “Isosthenuria” article, available under the CC BY-SA 4.0 licence.