keratomalacia
Keratomalacia is an eye disorder that results from vitamin A deficiency. Vitamin A is required to maintain specialized epithelia (such as in the cornea and conjunctiva).
Key facts
- Medical condition (new).name
- Keratomalacia
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Research
694 papers- Keratomalacia.Survey of ophthalmology · 1975
- Outcomes of treatments for keratomalacia in dogs and cats: a systematic review of the published literature including non-randomised controlled and non-controlled studies.The Journal of small animal practice · 2021
- Keratomalacia.The Journal of the Christian Medical Association of India · 1957
- Bilateral keratomalacia years after biliopancreatic diversion with duodenal switch surgery: A case of severe vitamin A deficiency and literature review.The Journal of international medical research · 2025
- Bilateral keratomalacia secondary to xerophthalmia.Nepalese journal of ophthalmology : a biannual peer-reviewed academic journal of the Nepal Ophthalmic Society : NEPJOPH · 2022
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Article
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Keratomalacia is an eye disorder that results from vitamin A deficiency. Vitamin A is required to maintain specialized epithelia (such as in the cornea and conjunctiva).
The precise mechanism is still not known, but vitamin A is necessary for the maintenance of the specialized epithelial surfaces of the body. A lack of vitamin A leads to atrophic changes in the normal mucosal surface, with loss of goblet cells, and replacement of the normal epithelium by an inappropriate keratinized stratified squamous epithelium. In addition, the substantia propria of the cornea breaks down and liquefies, resulting in keratomalacia.