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keratomalacia
EntityQ379418· pop 12· linked from 8 articles

keratomalacia

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Also known as vitamin A deficiency with keratomalacia, vitamin A deficiency with keratomalacia (disorder)

Keratomalacia is an eye disorder that results from vitamin A deficiency. Vitamin A is required to maintain specialized epithelia (such as in the cornea and conjunctiva).

Key facts

Medical condition (new).name
Keratomalacia

via Wikipedia infobox

Research

694 papers

via PubMed

Wikidata facts

Subclass of
disease
Show 5 more facts
health specialty
ophthalmology
ICD-9-CM
371.45
on focus list of Wikimedia project
WikiProject Medicine
Sources (3)

via Wikidata · CC0

~1 min read

Encyclopedic overview

4 sections
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Keratomalacia is an eye disorder that results from vitamin A deficiency. Vitamin A is required to maintain specialized epithelia (such as in the cornea and conjunctiva).

The precise mechanism is still not known, but vitamin A is necessary for the maintenance of the specialized epithelial surfaces of the body. A lack of vitamin A leads to atrophic changes in the normal mucosal surface, with loss of goblet cells, and replacement of the normal epithelium by an inappropriate keratinized stratified squamous epithelium. In addition, the substantia propria of the cornea breaks down and liquefies, resulting in keratomalacia.

Excerpted from Wikipedia’s “keratomalacia” article, available under the CC BY-SA 4.0 licence.