KLRG1
Sign in to saveAlso known as 2F1, CLEC15A, MAFA, MAFA-2F1, MAFA-L, MAFA-LIKE, killer cell lectin like receptor G1
Killer cell lectin-like receptor subfamily G member 1 is a protein that in humans is encoded by the KLRG1 gene.
Gene data
KLRG1- Name
- killer cell lectin like receptor G1
- Type
- protein-coding
- Position
- 8,950,044–9,010,760 (+)
- Aliases
- 2F1, CLEC15A, MAFA, MAFA-2F1, MAFA-L, MAFA-LIKE
- Ensembl
- ENSG00000139187
- RefSeq RNA
- NM_001329099.2, NM_001329101.2, NM_001329102.2, NM_001329103.2, NM_005810.4
- RefSeq protein
- NP_001316028.1, NP_001316030.1, NP_001316031.1, NP_001316032.1, NP_005801.3
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor (KLR) family, which is a group of transmembrane proteins preferentially expressed in NK cells. Studies in mice suggested that the expression of this gene may be regulated by MHC class I molecules. [provided by RefSeq, Jun 2016].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
killer cell lectin like receptor G1
- Symbol
- KLRG1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:8,950,044-9,165,627
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 4244
- exact match
- identifiers.org/ncbigene/10219
- genomic end
- 9163356
- genomic start
- 9102640
- cytogenetic location
- 12p13.31
Sources (4)
via Wikidata · CC0
~2 min read
Article
4 sectionsContents
- Function
- References
- Further reading
- External links
Killer cell lectin-like receptor subfamily G member 1 is a protein that in humans is encoded by the KLRG1 gene.
== Function ==