KPNA1

Name

karyopherin subunit alpha 1

Type

protein-coding

Aliases

IPOA5, NPI-1, RCH2, SRP1

The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import. This protein interacts with the recombination activating gene 1 (RAG1) protein and is a putative substrate of the RAG1 ubiquitin ligase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012].

via MyGene.info

Gene · Ensembl

karyopherin subunit alpha 1

Symbol

KPNA1

Biotype

Protein coding

Organism

Homo sapiens

Location

3:122,421,902-122,514,955

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Image

Protein KPNA1 PDB 2jdq.png

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