UBR5
Sign in to saveAlso known as DD5, EDD, EDD1, HYD, ubiquitin protein ligase E3 component n-recognin 5
E3 ubiquitin-protein ligase UBR5 is an enzyme that in humans is encoded by the UBR5 gene.
Gene data
UBR5- Name
- ubiquitin protein ligase E3 component n-recognin 5
- Type
- protein-coding
- Aliases
- DD5, EDD, EDD1, HYD, NEDSBH
This gene encodes a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin-protein ligases, targeting specific proteins for ubiquitin-mediated proteolysis. This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation. [provided by RefSeq, Jul 2008].
via MyGene.info
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 9295
- exact match
- identifiers.org/ncbigene/51366
- genomic end
- 102412759
- genomic start
- 102252273
- cytogenetic location
- 8q22.3
Sources (4)
via Wikidata · CC0
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Article
5 sectionsContents
- Function
- Interactions
- References
- Further reading
- External links
E3 ubiquitin-protein ligase UBR5 is an enzyme that in humans is encoded by the UBR5 gene.
== Function ==