LDB1
Sign in to saveAlso known as CLIM2, NLI, CLIM-2, LDB-1, LIM domain binding 1
LIM domain-binding protein 1 is a protein that in humans is encoded by the LDB1 gene.
Gene data
LDB1- Name
- LIM domain binding 1
- Type
- protein-coding
- Position
- 102,106,489–102,120,451 (−)
- Aliases
- CLIM-2, CLIM2, LDB-1, NLI
- Ensembl
- ENSG00000198728
- RefSeq RNA
- NM_001113407.3, NM_001321612.2, NM_003893.5, XM_017016867.2, XM_017016868.2
- RefSeq protein
- NP_001106878.1, NP_001308541.1, NP_003884.1, XP_016872356.1, XP_016872357.1
Enables LIM domain binding activity; RNA polymerase II-specific DNA-binding transcription factor binding activity; and enzyme binding activity. Involved in negative regulation of transcription, DNA-templated and positive regulation of transcription by RNA polymerase II. Located in chromatin. Part of beta-catenin-TCF complex. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
LIM domain binding 1
- Symbol
- LDB1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 10:102,106,489-102,120,451
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein LDB1 PDB 2XJY.png
Show 7 more facts
- HomoloGene ID
- 2891
- exact match
- identifiers.org/ncbigene/8861
- found in taxon
- Homo sapiens
- genomic end
- 102120368
- genomic start
- 102106489
- chromosome
- human chromosome 10
- cytogenetic location
- 10q24.32
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Interactions
- References
- Further reading
LIM domain-binding protein 1 is a protein that in humans is encoded by the LDB1 gene.
==Interactions== LDB1 has been shown to interact with other proteins such as LMO4, TCF3, TAL1 and CBFA2T3.
Excerpted from Wikipedia’s “LDB1” article, available under the CC BY-SA 4.0 licence.