Gene data
LDB1- Name
- LIM domain binding 1
- Type
- protein-coding
- Position
- 102,106,489–102,120,451 (−)
- Aliases
- CLIM-2, CLIM2, LDB-1, NLI
- Ensembl
- ENSG00000198728
- RefSeq RNA
- NM_001113407.3, NM_001321612.2, NM_003893.5, XM_017016867.2, XM_017016868.2
- RefSeq protein
- NP_001106878.1, NP_001308541.1, NP_003884.1, XP_016872356.1, XP_016872357.1
Enables LIM domain binding activity; RNA polymerase II-specific DNA-binding transcription factor binding activity; and enzyme binding activity. Involved in negative regulation of transcription, DNA-templated and positive regulation of transcription by RNA polymerase II. Located in chromatin. Part of beta-catenin-TCF complex. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
negative regulation of transcription by RNA polymerase IItranscription-dependent tethering of RNA polymerase II gene DNA at nuclear peripherytranscription-dependent tethering of RNA polymerase II gene DNA at nuclear peripherytranscription by RNA polymerase IInervous system developmentneuron differentiationneuron differentiationregulation of cell migration
Molecular function
Pathways
Transcriptional misregulation in cancer - Homo sapiens (human)Developmental BiologyGeneric Transcription PathwaySignaling by ROBO receptorsOlfactory Signaling PathwayAxon guidanceRNA Polymerase II TranscriptionGene expression (Transcription)Transcriptional regulation by RUNX1RUNX1 regulates transcription of genes involved in differentiation of HSCs
via MyGene.info
Gene · Ensembl
LIM domain binding 1
- Symbol
- LDB1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 10:102,106,489-102,120,451
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein LDB1 PDB 2XJY.png
Show 7 more facts
- HomoloGene ID
- 2891
- exact match
- identifiers.org/ncbigene/8861
- found in taxon
- Homo sapiens
- genomic end
- 102120368
- genomic start
- 102106489
- chromosome
- human chromosome 10
- cytogenetic location
- 10q24.32
Sources (4)
via Wikidata · CC0