🌐EnglishEnglishDeutschEspañolFrançaisItalianoالعربيةفارسی中文日本語EntityQ890470· pop 8· linked from 16 articlesLegius syndromerare genetic skin pigmentation disorder characterized by multiple cafe-au-lait maculesResearch131 papersRevised diagnostic criteria for neurofibromatosis type 1 and Legius syndrome: an international consensus recommendation.Genetics in medicine : official journal of the American College of Medical Genetics · 2021Legius Syndrome.1993Clinical and Genetic Findings in Children with Neurofibromatosis Type 1, Legius Syndrome, and Other Related Neurocutaneous Disorders.Genes · 2019Legius syndrome mutations in the Ras-regulator SPRED1 abolish its membrane localization and potentially cause neurodegeneration.The Journal of biological chemistry · 2024The RASopathies.Annual review of genomics and human genetics · 2013via PubMedConnectionsgenetic testingEntitycafé au lait spotEntityCategoriesGenodermatosesNeuro-cardio-facial-cutaneous syndromesRASopathies