Structure via PubChem · Public domain (PubChem)
レボフェナシルモルファン
Sign in to saveLevophenacylmorphan is a morphinan derivative that acts as an opioid agonist. It has potent analgesic effects and is around 10x more potent than morphine. Adverse effects associated with its use are those of the opioids as a whole, including pruritus, nausea, respiratory depression, euphoria and development of tolerance and dependence to its effects.
Chemical data
- Formula
- C24H27NO2
- Molecular weight
- 361.5 g/mol
- IUPAC name
- 2-[(1R,9R,10R)-4-hydroxy-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-17-yl]-1-phenylethanone
- SMILES
- C1CC[C@@]23CCN([C@@H]([C@@H]2C1)CC4=C3C=C(C=C4)O)CC(=O)C5=CC=CC=C5
- InChIKey
- RCYBMSQOSGJZLO-BGWNEDDSSA-N
- XLogP
- 4.2
- Polar surface area
- 40.5 Ų
- H-bond donors
- 1
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 361.204
Show 3 more facts
- chemical formula
- C₂₄H₂₇NO₂
- canonical SMILES
- C1CCC23CCN(C(C2C1)CC4=C3C=C(C=C4)O)CC(=O)C5=CC=CC=C5
- isomeric SMILES
- C1CC[C@@]23CCN([C@@H]([C@@H]2C1)CC4=C3C=C(C=C4)O)CC(=O)C5=CC=CC=C5
Sources (2)
via Wikidata · CC0