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EntityQ1827605· pop 24· linked from 23 articles

Also known as lipoedema, lipödem, lipalgia, adiposalgia, adipoalgesia, adiposis dolorosa, lipomatosis dolorosa of the legs, lipohypertrophy dolorosa

Key facts

Medical condition.name
Lipedema
Medical condition.image
Lipedema, type III.jpg
Medical condition.caption
Lipedema, type III, stage 1.
Medical condition.synonyms
Lipoedema, lipödem, lipalgia, adiposalgia, adipoalgesia, adiposis dolorosa, lipomatosis dolorosa of the legs, lipohypertrophy dolorosa, painful column leg, painful lipedema syndrome
Medical condition.field
Vascular medicine
Medical condition.symptoms
Increased fat deposits under the skin in the legs, increased extracellular fluid, inflammation, easy bruising, pain
Medical condition.causes
Unknown
Medical condition.risks
Family member with the condition
Medical condition.differential
Lipohypertrophy, chronic venous insufficiency, lymphedema
Medical condition.treatment
Physiotherapy, exercise compression stockings, emollients, liposuction
Medical condition.frequency
Up to 11% of women

via Wikipedia infobox

Research

746 papers

via PubMed

~8 min read

Encyclopedic overview

15 sections
Contents
  • Signs and symptoms
  • Associated conditions
  • Cause
  • Diagnosis
  • Differential diagnosis
  • Lipedema stages
  • Similar conditions
  • Lipo-lymphedema
  • Dercum's disease
  • Treatment
  • Prognosis
  • Epidemiology
  • History
  • See also
  • References

Lipedema is a condition that is almost exclusively found in women and results in enlargement of both legs due to deposits of fat under the skin. Women of any weight may be affected and the fat is resistant to traditional weight-loss methods. There is no cure and typically it gets worse over time, pain may be present, and people bruise more easily. Over time mobility may be reduced, and due to reduced quality of life, people often experience depression. In severe cases the trunk and upper body may be involved.

The cause is unknown but is believed to involve genetic and hormonal factors that regulate the lymphatic system, thus blocking the return of fats to the bloodstream. It often runs in families. Other conditions that may present similarly include lipohypertrophy, chronic venous insufficiency, and lymphedema. It is commonly misdiagnosed.

Excerpted from Wikipedia’s “lipedema” article, available under the CC BY-SA 4.0 licence.