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ezetimibe
Ezetimibe, sold under the brand name Zetia among others, is a medication used to treat high blood cholesterol and certain other lipid abnormalities. Generally it is used together with dietary changes and a statin. Alone, it is less preferred than a statin. It is taken by mouth. It is also available in the fixed-dose combinations ezetimibe/simvastatin, ezetimibe/atorvastatin, ezetimibe/rosuvastatin, and ezetimibe/bempedoic acid.
Key facts
- Drug.Watchedfields
- changed
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- 461098524
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- Ezetimibe.svg
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- Above: molecular structure of ezetimibe Below: 3D representation of an ezetimibe molecule
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- Zetia, others
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- a603015
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- Ezetimibe
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- B3
- Drug.routes_of_administration
- By mouth
~5 min read
Article
8 sectionsContents
- Medical uses
- Contraindications
- Adverse effects
- Overdose
- Pharmacology
- Mechanism of action
- Pharmacokinetics
- References
Ezetimibe, sold under the brand name Zetia among others, is a medication used to treat high blood cholesterol and certain other lipid abnormalities. Generally it is used together with dietary changes and a statin. Alone, it is less preferred than a statin. It is taken by mouth. It is also available in the fixed-dose combinations ezetimibe/simvastatin, ezetimibe/atorvastatin, ezetimibe/rosuvastatin, and ezetimibe/bempedoic acid.
The most commonly reported adverse events include upper respiratory tract infections, joint pain, diarrhea, and tiredness. Serious side effects may include anaphylaxis, liver problems, depression, and muscle breakdown. Use in pregnancy and breastfeeding is of unclear safety. Ezetimibe works by decreasing cholesterol absorption in the intestines.