liposome
Sign in to savethumb|right|Scheme of a liposome formed by phospholipids in an [[aqueous solution.]] thumb|right|Liposomes are composite structures made of phospholipids and may contain small amounts of other molecules. Though liposomes can vary in size from low micrometer range to tens of micrometers, unilamellar liposomes, as pictured here, are typically in the lower size range with various targeting ligands attached to their surface allowing for their surface-attachment and accumulation in pathological areas for treatment of disease.
Research
90,220 papers- Liposome composition in drug delivery design, synthesis, characterization, and clinical application.Advanced drug delivery reviews · 2021
- Liposome-Based Interventions in Knee Osteoarthritis.Small (Weinheim an der Bergstrasse, Germany) · 2025
- Excipient-related impurities in liposome drug products.International journal of pharmaceutics · 2024
- Liposome opsonization.Journal of liposome research · 2005
- Recent advances in liposome-based targeted cancer therapy.Journal of liposome research · 2024
via PubMed
Article
10 sectionsContents
- Discovery
- Mechanism
- Encapsulation in liposomes
- Delivery
- Dietary and nutritional supplements
- Manufacturing
- Prospect
- See also
- References
- External links
thumb|right|Scheme of a liposome formed by phospholipids in an [[aqueous solution.]] thumb|right|Liposomes are composite structures made of phospholipids and may contain small amounts of other molecules. Though liposomes can vary in size from low micrometer range to tens of micrometers, unilamellar liposomes, as pictured here, are typically in the lower size range with various targeting ligands attached to their surface allowing for their surface-attachment and accumulation in pathological areas for treatment of disease.
A liposome is a small artificial vesicle, spherical in shape, having at least one lipid bilayer. Due to their hydrophobicity and/or hydrophilicity, biocompatibility, particle size and many other properties, liposomes can be used as drug delivery vehicles for administration of pharmaceutical drugs and nutrients, such as lipid nanoparticles in mRNA vaccines, and DNA vaccines. Liposomes can be prepared by disrupting biological membranes (such as by sonication).