doxorubicin
Sign in to saveDoxorubicin, sold under the brand name Adriamycin among others, is a chemotherapy medication used to treat cancer. This includes breast cancer, bladder cancer, Kaposi's sarcoma, lymphoma, and acute lymphocytic leukemia. It is often used together with other chemotherapy agents. Doxorubicin is given by injection into a vein.
Key facts
- Drug.Verifiedfields
- changed
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 458446335
- Drug.image
- Doxorubicin.svg
- Drug.image_class
- skin-invert-image
- Drug.image2
- Doxorubicin ball-and-stick model from xtal 2018.png
- Drug.image_class2
- bg-transparent
- Drug.tradename
- Adriamycin, Caelyx, Myocet, others
- Drug.MedlinePlus
- a682221
- Drug.licence_EU
- yes
- Drug.DailyMedID
- Doxorubicin
- Drug.pregnancy_AU
- D
- Drug.routes_of_administration
- intravenous, intravesical
- Drug.ATC_prefix
- L01
- Drug.ATC_suffix
- DB01
- Drug.biosimilars
- Zolsketil pegylated liposomal, Celdoxome pegylated liposomal
- Drug.legal_AU
- S4
- Drug.legal_CA
- Rx-only
via Wikipedia infobox
Research
94,892 papers- Doxorubicin alone versus doxorubicin with trabectedin followed by trabectedin alone as first-line therapy for metastatic or unresectable leiomyosarcoma (LMS-04): a randomised, multicentre, open-label phase 3 trial.The Lancet. Oncology · 2022
- An overview of doxorubicin formulations in cancer therapy.Journal of cancer research and therapeutics · 2014
- A comprehensive review on doxorubicin: mechanisms, toxicity, clinical trials, combination therapies and nanoformulations in breast cancer.Drug delivery and translational research · 2025
- Liposomal doxorubicin.Journal of drug targeting · 1996
- Doxorubicin Action on Mitochondria: Relevance to Osteosarcoma Therapy?Current drug targets · 2018
via PubMed
Article
18 sectionsContents
- Medical uses
- Side effects
- Cardiotoxicity
- Other
- Liposomal formulations
- Biosynthesis
- Mechanism of action
- History
- Society and culture
- Legal status
- Names
- Formulations
- Popular culture
- Research
- Antimalarial activity
- Fluorescence
- References
- External links
Doxorubicin, sold under the brand name Adriamycin among others, is a chemotherapy medication used to treat cancer. This includes breast cancer, bladder cancer, Kaposi's sarcoma, lymphoma, and acute lymphocytic leukemia. It is often used together with other chemotherapy agents. Doxorubicin is given by injection into a vein.
Common side effects include hair loss, bone marrow suppression, vomiting, rash, and inflammation of the mouth. Other serious side effects may include allergic reactions such as anaphylaxis, heart damage, tissue damage at the site of injection, radiation recall, and treatment-related leukemia. People often experience red discoloration of the urine for a few days. Doxorubicin is in the anthracycline and antitumor antibiotic family of medications. It works in part by interfering with the function of DNA.
Gallery (4)
Connections
Categories
AnthracyclinesAnthraquinone glycosidesChemical articles with multiple CAS registry numbersChemical articles with multiple ChEBIsChemical articles with multiple PubChem CIDsChemicals using indexlabelsCYP2D6 inhibitorsDNA intercalatersDrugboxes which contain changes to verified fieldsDrugboxes which contain changes to watched fieldsDrug has EMA link