Gene data
LMO2- Name
- LIM domain only 2
- Type
- protein-coding
- Position
- 33,858,563–33,892,076 (−)
- Aliases
- LMO-2, RBTN2, RBTNL1, RHOM2, TTG2
- Ensembl
- ENSG00000135363
- RefSeq RNA
- NM_001142315.2, NM_001142316.2, NM_005574.4, XM_017017733.2, XM_047426944.1
- RefSeq protein
- NP_001135787.1, NP_001135788.1, NP_005565.2, XP_016873222.1, XP_047282900.1
LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Nov 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
LIM domain only 2
- Symbol
- LMO2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:33,858,563-33,892,076
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein LDB1 PDB 2XJY.png
Show 8 more facts
- HomoloGene ID
- 4072
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/4005
- genomic end
- 33892076
- genomic start
- 33880122
- chromosome
- human chromosome 11
- cytogenetic location
- 11p13
- expressed in
- synovial membrane
Sources (4)
via Wikidata · CC0