LSM1
Sign in to saveAlso known as CASM, YJL124C, LSM1 homolog, mRNA degradation associated
U6 snRNA-associated Sm-like protein LSm1 is a protein that in humans is encoded by the LSM1 gene.
Gene data
LSM1- Name
- LSM1 homolog, mRNA degradation associated
- Type
- protein-coding
- Aliases
- CASM, FICUS, YJL124C
This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Increased expression of this gene may play a role in cellular transformation and the progression of several malignancies including lung cancer, mesothelioma and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, Nov 2011].
via MyGene.info
Wikidata facts
Show 3 more facts
- HomoloGene ID
- 40945
- exact match
- identifiers.org/ncbigene/27257
- cytogenetic location
- 8p11.23
Sources (3)
via Wikidata · CC0
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Article
3 sectionsContents
- Function
- References
- Further reading
U6 snRNA-associated Sm-like protein LSm1 is a protein that in humans is encoded by the LSM1 gene.
== Function ==