metagenomics
Sign in to savethumb|upright=1.5|In metagenomics, the genetic materials (DNA, C) are extracted directly from samples taken from the environment (e.g. soil, sea water, human gut, A) after filtering (B), and are sequenced (E) after multiplication by cloning (D) in an approach called [[shotgun sequencing. These short sequences can then be put together again using assembly methods (F) to deduce the individual genomes or parts of genomes that constitute the original environmental sample. This information can then be used to study the species diversity and functional potential of the microbial community of the env
Research
52,638 papers- What Is Metagenomics Teaching Us, and What Is Missed?Annual review of microbiology · 2020
- Genome-resolved metagenomics using environmental and clinical samples.Briefings in bioinformatics · 2021
- Metagenomic tools in microbial ecology research.Current opinion in biotechnology · 2021
- Metagenomics: Probing pollutant fate in natural and engineered ecosystems.Biotechnology advances · 2016
- CheckM: assessing the quality of microbial genomes recovered from isolates, single cells, and metagenomes.Genome research · 2015
via PubMed
~34 min read
Encyclopedic overview
29 sectionsContents
- Etymology
- History
- Sequencing
- Shotgun metagenomics
- High-throughput sequencing
- Sequencing depth
- Bioinformatics
- Sequence pre-filtering
- Assembly
- Species diversity
- Gene prediction
- Comparative metagenomics
- Data analysis
- Community metabolism
- Metatranscriptomics
- Viruses
- Applications
- Agriculture
- Biofuel
- Biotechnology
- Ecology
- Environmental remediation
- Gut microbe characterization
- Infectious disease diagnosis
- Arbovirus surveillance
- Dietary estimation
- See also
- References
- External links
thumb|upright=1.5|In metagenomics, the genetic materials (DNA, C) are extracted directly from samples taken from the environment (e.g. soil, sea water, human gut, A) after filtering (B), and are sequenced (E) after multiplication by cloning (D) in an approach called [[shotgun sequencing. These short sequences can then be put together again using assembly methods (F) to deduce the individual genomes or parts of genomes that constitute the original environmental sample. This information can then be used to study the species diversity and functional potential of the microbial community of the environment.]]
Metagenomics is the study of all genetic material from all organisms in a particular environment, providing insights into their composition, diversity, and functional potential. Metagenomics has allowed researchers to profile the microbial composition of environmental and clinical samples without the need for time-consuming culture of individual species.
Excerpted from Wikipedia’s “metagenomics” article, available under the CC BY-SA 4.0 licence.