Structure via PubChem · Public domain (PubChem)
methyl isocyanate
Sign in to saveAlso known as isocyanatomethane, methyl carbonimide, MIC, Methylcarbylamine, isocyanic acid methyl ester
chemical compound
Chemical data
- Formula
- C2H3NO
- Molecular weight
- 57.05 g/mol
- IUPAC name
- methylimino(oxo)methane
- SMILES
- CN=C=O
- InChIKey
- HAMGRBXTJNITHG-UHFFFAOYSA-N
- XLogP
- 1.1
- Polar surface area
- 29.4 Ų
- H-bond donors
- 0
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
425 papers- Methyl isocyanate and carcinogenesis: bridgeable gaps in scientific knowledge.Asian Pacific journal of cancer prevention : APJCP · 2012
- Toxicology of methyl isocyanate.Reviews of environmental contamination and toxicology · 1988
- Methyl isocyanate exposure.Journal of occupational and environmental medicine · 1998
- Methyl isocyanate: a review of health effects research since Bhopal.Fundamental and applied toxicology : official journal of the Society of Toxicology · 1987
- Reaction mechanisms for methyl isocyanate (CH(3)NCO) gas-phase degradation.Journal of hazardous materials · 2024
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Has part
- carbon
- Mass
- 57.021464
Show 19 more facts
- melting point
- -45
- canonical SMILES
- CN=C=O
- flash point
- 19
- NIOSH Pocket Guide ID
- 0423
- density
- 0.96
- immediately dangerous to life or health
- 7.02
- boiling point
- 39.5
- vapor pressure
- 348
- solubility
- 10
- lower flammable limit
- 5.3
- upper flammable limit
- 26
- ionization energy
- 10.67
- time-weighted average exposure limit
- 0.05
- ceiling exposure limit
- 0.05
- chemical formula
- C₂H₃NO
- Commons category
- Methyl isocyanate
- different from
- methyl isocyanide
- electric dipole moment
- 2.8
- facet of
- Bhopal disaster
via Wikidata · CC0
~12 min read
Encyclopedic overview
Methyl isocyanate (MIC) is an organic compound with the molecular formula CH3NCO. Synonyms are isocyanatomethane and methyl carbylamine. Methyl isocyanate is a chemical intermediate in the Hofmann rearrangement of acetamide and the production of carbamate pesticides (such as carbaryl, carbofuran, methomyl, and aldicarb). It has also been used in the production of rubbers and adhesives. As an extremely toxic and irritating compound, it is very hazardous to human health. MIC was the principal toxicant involved in the Bhopal gas disaster, which short-term killed 4,000–8,000 people and caused permanent injury and premature deaths to approximately 15,000–20,000. It is also a very potent lachrymatory agent.
Physical properties
Excerpted from Wikipedia’s “methyl isocyanate” article, available under the CC BY-SA 4.0 licence.