MICU1

Also known as CALC, CBARA1, EFHA3, MPXPS, mitochondrial calcium uptake 1, ara CALC

Calcium-binding atopy-related autoantigen 1 is a protein that in humans is encoded by the CBARA1 gene.

Gene data

MICU1

Name: mitochondrial calcium uptake 1
Type: protein-coding
Aliases: CALC, CBARA1, EFHA3, MPXPS, ara CALC

This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2013].

via MyGene.info