mirfentanil
Sign in to saveMirfentanil is a fentanyl derivative with strong selectivity for the μ opioid receptor. At lower doses, it antagonizes the analgesic effects of alfentanil and substitutes for naloxone in morphine-treated monkeys; however, it also reverses naloxone-precipitated withdrawal in pigeons trained to discriminate morphine from naloxone.
In the Vinony graph
Within Vinony's link graph, mirfentanil is referenced by 6 other articles, and connects out to (+)-catechin, butorphanol and OPRM1.
It sits within the topics 2-Furyl compounds, Aminopyrazines and Carboxamides.
Its subject is documented across 5 Wikipedia language editions.
Wikidata facts
- Mass
- 376.189926
Show 3 more facts
- canonical SMILES
- C1CN(CCC1N(C2=NC=CN=C2)C(=O)C3=CC=CO3)CCC4=CC=CC=C4
- chemical formula
- C₂₂H₂₄N₄O₂
- Commons category
- Mirfentanil
Sources (2)
via Wikidata · CC0
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Encyclopedic overview
4 sectionsContents
- Synthesis
- See also
- References
- External links
Mirfentanil is a fentanyl derivative with strong selectivity for the μ opioid receptor. At lower doses, it antagonizes the analgesic effects of alfentanil and substitutes for naloxone in morphine-treated monkeys; however, it also reverses naloxone-precipitated withdrawal in pigeons trained to discriminate morphine from naloxone.
At high doses, it exhibits analgesic activity which is not fully reversed by opioid antagonists, suggesting that the drug has both opioid and non-opioid mechanisms of action.
Excerpted from Wikipedia’s “mirfentanil” article, available under the CC BY-SA 4.0 licence.