MOAP1
Sign in to saveAlso known as MAP-1, PNMA4, modulator of apoptosis 1
Genen från arten Homo sapiens
Gene data
MOAP1- Name
- modulator of apoptosis 1
- Type
- protein-coding
- Position
- 93,182,176–93,184,930 (−)
- Aliases
- MAP-1, PNMA4
- Ensembl
- ENSG00000165943
- RefSeq RNA
- NM_022151.5
- RefSeq protein
- NP_071434.2
The protein encoded by this gene was identified by its interaction with apoptosis regulator BAX protein. This protein contains a Bcl-2 homology 3 (BH3)-like motif, which is required for the association with BAX. When overexpressed, this gene has been shown to mediate caspase-dependent apoptosis. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
extrinsic apoptotic signaling pathway via death domain receptorsintrinsic apoptotic signaling pathway in response to DNA damageregulation of apoptotic processpositive regulation of apoptotic processprotein insertion into mitochondrial membranepositive regulation of release of cytochrome c from mitochondriaapoptotic signaling pathwayextrinsic apoptotic signaling pathway in absence of ligand
Molecular function
via MyGene.info
Gene · Ensembl
modulator of apoptosis 1
- Symbol
- MOAP1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 14:93,182,176-93,184,930
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 11154
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/64112
- chromosome
- human chromosome 14
- genomic start
- 93182199
- genomic end
- 93184923
- cytogenetic location
- 14q32.12
Sources (4)
via Wikidata · CC0