MOAP1
Sign in to saveAlso known as MAP-1, PNMA4, modulator of apoptosis 1
Modulator of apoptosis 1 is a protein that in humans is encoded by the MOAP1 gene.
In the Vinony graph
Within Vinony's link graph, MOAP1 is referenced by 3 other articles, and connects out to PubMed, human chromosome 14 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 14.
Its subject is documented across 6 Wikipedia language editions.
Gene data
MOAP1- Name
- modulator of apoptosis 1
- Type
- protein-coding
- Position
- 93,182,176–93,184,930 (−)
- Aliases
- MAP-1, PNMA4
- Ensembl
- ENSG00000165943
- RefSeq RNA
- NM_022151.5
- RefSeq protein
- NP_071434.2
The protein encoded by this gene was identified by its interaction with apoptosis regulator BAX protein. This protein contains a Bcl-2 homology 3 (BH3)-like motif, which is required for the association with BAX. When overexpressed, this gene has been shown to mediate caspase-dependent apoptosis. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
modulator of apoptosis 1
- Symbol
- MOAP1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 14:93,182,176-93,184,930
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 11154
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/64112
- chromosome
- human chromosome 14
- genomic start
- 93182199
- genomic end
- 93184923
- cytogenetic location
- 14q32.12
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Modulator of apoptosis 1 is a protein that in humans is encoded by the MOAP1 gene.
The protein encoded by this gene was identified by its interaction with apoptosis regulator BAX protein. This protein contains a Bcl-2 homology 3 (BH3)-like motif, which is required for the association with BAX. When overexpressed, this gene has been shown to mediate caspase-dependent apoptosis.
Excerpted from Wikipedia’s “MOAP1” article, available under the CC BY-SA 4.0 licence.