MOPP療法

Also known as Vincaleukoblastine, 22-oxo-, mixt. with 2-chloro-N-(2-chloroethyl)-N-methylethanamine hydrochloride (1:1), 17,21-dihydroxypregna-1,4-diene-3,11,20-trione and N-(1-methylethyl)-4-[(2-methylhydrazino)methyl]benzamide, Vincristine-prednisone-nitrogen mustard-procarbazine mixt, Nitrogen mustard regimen with prednisone, procarbazine and vincristine, Vincristine-prednisone-nitrogen mustard-procarbazine mixt.

chemotherapy regimen

Chemical data

Formula: C84H113Cl3N8O16
Molecular weight: 1597.2 g/mol
IUPAC name: 2-chloro-N-(2-chloroethyl)-N-methylethanamine;(8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione;methyl (1R,10S,11R,12R)-11-acetyloxy-12-ethyl-4-[(13S,15S,17S)-17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-8-formyl-10-hydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate;4-[(2-methylhydrazinyl)methyl]-N-propan-2-ylbenzamide;hydrochloride
SMILES: CC[C@@]1(C[C@@H]2C[C@@](C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)[C@]78CCN9C7[C@@](C=CC9)([C@H]([C@@](C8N6C=O)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O.CC(C)NC(=O)C1=CC=C(C=C1)CNNC.C[C@]12CC(=O)[C@H]3[C@H]([C@@H]1CC[C@@]2(C(=O)CO)O)CCC4=CC(=O)C=C[C@]34C.CN(CCCl)CCCl.Cl
InChIKey: SVYBPMMLNVMOPS-WBQZPATFSA-N
Polar surface area: 319 Å²
H-bond donors: 9
H-bond acceptors: 21
Formal charge: 0